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What is P53? How does it help fight cancer?

Ingrained in human DNA are particular genes that help prevent cells from becoming cancerous. One of the most important tumour-suppressor genes is the p53 gene.

For many cancers, the p53 gene is faulty. Which means that cells are no longer naturally resistant to becoming cancerous. Observations conducted by doctors have indicated that half of human cancer cases involve mutated p53 genes. Moreover, p53 genes which aren’t functioning properly aid cancer to spread faster and be even more resistant to treatment.

At Integrated Health Systems, we offer a gene therapy programme. We replace the mutated p53 genes in cancer cells with a healthy version. As such, this rapidly improves the treatment of many forms of cancer.

What is head and neck cancer?

Head and neck cancers are a group of cancers that occur in the following locations:

  • Mouth
  • Nose
  • Throat
  • Larynx
  • Sinuses
  • Salivary glands

P53 is known as a tumour suppressor protein, providing a natural cancer defence in the body. In cancer cells, the P53 tumour suppressor protein is normally turned off or has become mutated. And as a result, the cancer can go un-noticed.

Our gene therapy treatments allow the P53 tumour suppressor protein to once again become fully effective. This allows the body to eradicate the cancer in a natural way. We are proud to say that our treatments achieve a 77% response rate when combined with chemotherapy and radiotherapy. Moreover, our treatments have reported to improve efficacy and quality of life for patients in clinical trials and have been used successfully in over 30,000 patients around the world.

Who is Dr. Jason Williams?

Dr. Jason Williams has been delivering gene therapy to patients for over 14 years. Furthermore, he was one of the first doctors to deliver P53 gene therapy to cancer patients in North America. A number of new cancer therapies have been developed over the past decade. Such as:

  • Gene therapy
  • Tumour ablation
  • Immunotherapy

These treatments have been continually refined, updated and perfected, offering not only the best long term outcomes, but being able to offer patients the highest level of care also. At Integrated Health Systems, our primary concern is your health and wellbeing. We understand that this period of your life can be testing, which is why we only deliver the very best level of care, with the aim of fighting your cancer completely. We wish you a long and healthy future and look forward to working with you.

Three steps to a healthy you



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