There is no Parkinson’s cure in sight and symptoms gradually worsen with time. While tremors are the most widely recognized Parkinson’s symptom, stiffness, and slowing of movement are also common. Although there are a number of medications that can allay symptoms, there are no effective preventive or curative measures for PD at this time. Gene therapy and cell therapy are two promising routes.
Integrated Health System’s gene therapy targeting neurodegeneration utilizes an adeno-associated virus (AAV) vector platform modified for the enhanced delivery to neural tissue. The genes to treat the disorder are inserted into the delivery method, which then delivers the genes of interest to the patient’s cells. In recent years, AAV gene therapies have been tested in humans with great success, and no evidence of adverse effects has been visible. There are numerous clinical trials currently being conducted with AAV gene therapy for many diseases. This is why telomerase shows promise for Alzheimer’s and Parkinson’s.
Dr Williams CMO is a radiologist. He obtained his medical degree from Louisiana State University and has also completed an internship in Internal Medicine at The University of South Alabama. He is passionate about gene and cellular therapies, administered under image guidance. Image guided cancer therapies are also one of his interests. For several years, he did research with adenoviral vector technology used to treat cancer. He was selected for the RSNA Research Fellow Award. He has completed training in image guided cancer and spine procedures, and is board certified by the American Board of Radiology. He has research interests in gene therapy and stem cell reprogramming, as well as using CT and MRI for minimally invasive procedures related to the spine and cancer.
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