Parkinson’s Disease (PD) is a progressive neurodegenerative disease that affects movement. More than 10 million people around the world are living with Parkinson’s. Over 60,000 new diagnoses are made each year in the United States.

There is no Parkinson’s cure in sight and symptoms gradually worsen with time. While tremors are the most widely recognized Parkinson’s symptom, stiffness, and slowing of movement are also common. Although there are a number of medications that can allay symptoms, there are no effective preventive or curative measures for PD at this time. Gene therapy and cell therapy are two promising routes.



Integrated Health System’s gene therapy targeting neurodegeneration utilizes an adeno-associated virus (AAV) vector platform modified for the enhanced delivery to neural tissue. The genes to treat the disorder are inserted into the delivery method, which then delivers the genes of interest to the patient’s cells. In recent years, AAV gene therapies have been tested in humans with great success, and no evidence of adverse effects has been visible. There are numerous clinical trials currently being conducted with AAV gene therapy for many diseases. This is why telomerase shows promise for Alzheimer’s and Parkinson’s.

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