Pgc-1α and Mitochondria


Integrated Health Systems strives to stay on the cutting edge of regenerative medicine. PGC-1α is the master regulator of mitochondrial biogenesis, the creation of new mitochondria. Mitochondrial health is critical to cellular health. Over 90% of the energy produced in your body comes from them, which is why they are called the “powerhouses” of our cells. Besides making new mitochondria, PGC-1α: 

Cells start to fail when mitochondria begin failing, resulting in diminished performance. Low energy levels and even chronic fatigue are, in part, the result of increasing mitochondrial dysfunction over time. It can be activated by exercise, cold temperatures, and fasting, but like so many other things, levels decline over time – even if you’re doing everything right. There are mitochondria supplements on the market that claim to boost the creation of new mitochondria, but none of them do it as effectively as the direct activation of PGC-1α through gene therapy. 



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